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BDBM18240 2,4-diamino-5-deazapteridine, 9::Piritrexim analogue,32::ethyl 6-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl}methyl)-4-methoxyphenoxy]hexanoate

SMILES: CCOC(=O)CCCCCOc1ccc(c(c1)Cc2cnc3c(c2C)c(nc(n3)N)N)OC

InChI Key: InChIKey=FGBRLIYQKRWOSO-UHFFFAOYSA-N

Data: 5 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18240   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydrofolate reductase


(Pneumocystis carinii)		BDBM18240
PNG
(ethyl 6-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyri...)		GoogleScholar
UniChem
n/an/a 35n/an/an/an/a7.437


TBA



Citation and Details
More data for this
Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase


(Toxoplasma gondii)		BDBM18240
PNG
(ethyl 6-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyri...)		GoogleScholar
UniChem
n/an/a 13n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Mycobacterium avium)		BDBM18240
PNG
(ethyl 6-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyri...)		GoogleScholar
UniChem
n/an/a 12n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Rat)		BDBM18240
PNG
(ethyl 6-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyri...)		GoogleScholar
UniChem
n/an/a 21n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)		BDBM18240
PNG
(ethyl 6-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyri...)		GoogleScholar
UniChem
n/an/a 1.85E+3n/an/an/an/a7.025


TBA



Citation and Details
More data for this
Ligand-Target Pair