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BDBM182774 US9145414, 48

SMILES: COc1ccc2sc(Nc3nc(N[C@@H]4CCCC[C@@H]4N)nnc3C(N)=O)c(C)c2c1

InChI Key: InChIKey=VVRDDABYTUFNHQ-DUXBJXIBNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182774   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM182774
PNG
(US9145414, 48)
Show SMILES COc1ccc2sc(Nc3nc(N[C@@H]4CCCC[C@@H]4N)nnc3C(N)=O)c(C)c2c1
Show InChI InChI=1/C20H25N7O2S/c1-10-12-9-11(29-2)7-8-15(12)30-19(10)24-18-16(17(22)28)26-27-20(25-18)23-14-6-4-3-5-13(14)21/h7-9,13-14H,3-6,21H2,1-2H3,(H2,22,28)(H2,23,24,25,27)/t13-,14+/s2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.270n/an/an/an/a7.525



Taiho Pharmaceutical Co., Ltd

US Patent


Assay Description
The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...


US Patent US9145414 (2015)


BindingDB Entry DOI: 10.7270/Q2513X18
More data for this
Ligand-Target Pair