BDBM183125 US9150546, I-277::US9688643, I-277::US9718790, I-0277

SMILES CCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key InChIKey=ZFOLLFDANAKBTB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 183125   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM183125(US9150546, I-277 | US9688643, I-277 | US9718790, I...)
Affinity DataIC50:  38nMpH: 7.5 T: 2°CAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM183125(US9150546, I-277 | US9688643, I-277 | US9718790, I...)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at human P2X3 receptor expressed in rat C6-BU-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM183125(US9150546, I-277 | US9688643, I-277 | US9718790, I...)
Affinity DataIC50:  38nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM183125(US9150546, I-277 | US9688643, I-277 | US9718790, I...)
Affinity DataIC50:  38nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...More data for this Ligand-Target Pair
In DepthDetails US Patent