BDBM18355 (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol::CHEMBL1029::MIGLUSTAT::N-Butyl-DNJ::US20230339856, Compound NB-DNJ::US9181184, 5

SMILES: CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key: InChIKey=UQRORFVVSGFNRO-UHFFFAOYSA-N

Data: 5 KI  56 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 61 hits for monomerid = 18355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ceramide glucosyltransferase (Mouse)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen debranching enzyme (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Maltase-glucoamylase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Mouse)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-galactosidase (Mouse)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase (Mouse)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Mouse)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Putative alpha-glucosidase (Rice)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lactase/phlorizin hydrolase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Trehalase (Pig)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Trehalase (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lactase/phlorizin hydrolase (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.74E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.99E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.59E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ceramide glucosyltransferase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	4.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Mouse)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.18E+4	n/a	n/a	4.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase (Mouse)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid/Non-lysosomal glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Trehalase (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Maltase-glucoamylase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lactase/phlorizin hydrolase (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-mannosidase 2C1 (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-mannosidase (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-mannosidase 2 (Rat)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-lysosomal glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Human)	BDBM18355 (N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair