BDBM18359 (2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-methylpiperidine-3,4,5-triol::CHEMBL503021::alpha-1-C-Methyl-DNJ

SMILES C[C@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=ZEWFPWKROPWRKE-XUUWZHRGSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18359   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18359((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-methylpiperid...)
Affinity DataIC50:  9.00E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Hokuriku University

LigandPNGBDBM18359((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-methylpiperid...)
Affinity DataIC50:  2.80E+4nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18359((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-methylpiperid...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of rat intestinal maltase assessed as D-glucose release after 30 mins by Glucose B-testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18359((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-methylpiperid...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of rat liver lysosome alpha-glucosidase assessed as D-glucose release after 30 mins by Glucose B-testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18359((2R,3R,4R,5S,6R)-2-(hydroxymethyl)-6-methylpiperid...)
Affinity DataIC50:  2.60E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as p-nitrophenol release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed