BDBM183643 US9150519, 1-5

SMILES Oc1ccc(NC(=O)c2cc(NC3CCCCC3)ncn2)c2ccccc12

InChI Key InChIKey=ODJZPCPILLDSHR-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 183643   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM183643(US9150519, 1-5)
Affinity DataKi:  540nM ΔG°:  -7.94kcal/molepH: 7.4 T: 2°CAssay Description:Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells were suspended in 50 mM TRI...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM183643(US9150519, 1-5)
Affinity DataEC50: >3.00E+4nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM183643(US9150519, 1-5)
Affinity DataEC50:  540nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails US Patent