BDBM18376 (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid::Cerivastatin::cid_446156

SMILES: COCc1c(nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)c1-c1ccc(F)cc1)C(C)C

InChI Key: InChIKey=SEERZIQQUAZTOL-UHFFFAOYSA-N

Data: 2 KI  4 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 18376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM18376 ((3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	7.2	37
TBA									Citation and Details
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3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM18376 ((3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	1.70	n/a	n/a	7.2	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Rat)	BDBM18376 ((3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80	n/a	2.30	n/a	n/a	7.0	37
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Cystic fibrosis transmembrane conductance regulator (Human)	BDBM18376 ((3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Human)	BDBM18376 ((3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM18376 ((3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Rat)	BDBM18376 ((3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair