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BDBM184275 US9150577, 145

SMILES: CC(C)c1cccc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)c1

InChI Key: InChIKey=DUCUIRXEVXZKPK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 184275   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (Human))
BDBM184275
PNG
(US9150577, 145)
Show SMILES CC(C)c1cccc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)c1
Show InChI InChI=1S/C22H23N3O2/c1-14(2)15-5-3-6-18(11-15)24-21(26)17-8-7-16-12-20-22(27)23-9-4-10-25(20)19(16)13-17/h3,5-8,11-14H,4,9-10H2,1-2H3,(H,23,27)(H,24,26)
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KEGG

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 140n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair