BDBM18506 6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-2-ylmethyl}pteridine-2,4-diamine::CHEMBL301769::Pteridine compound, 17

SMILES: c1ccc2c(c1)C=Cc3ccccc3N2Cc4cnc5c(n4)c(nc(n5)N)N

InChI Key: InChIKey=NXCCIJQEAKMFGW-UHFFFAOYSA-N

Data: 11 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 18506   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	7.0	25
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Dihydrofolate reductase (Mycobacterium avium)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Rat)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Pneumocystis carinii)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (Toxoplasma gondii)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (Toxoplasma gondii)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Rat)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Human)	BDBM18506 (6-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
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