BDBM18525 Bicalutamide::CHEMBL409::N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorobenzene)sulfonyl]-2-hydroxy-2-methylpropanamide::US11046713, Example Bicalutamide::US20230382870, Bicalutumide::US9126941, Bicalutamide::US9682960, CAS

SMILES: C[C@](CS(=O)(=O)c1ccc(cc1)F)(C(=O)Nc2ccc(c(c2)C(F)(F)F)C#N)O

InChI Key: InChIKey=LKJPYSCBVHEWIU-UHFFFAOYSA-N

Data: 25 KI  70 IC50  7 EC50

PDB links: 10 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 99 hits for monomerid = 18525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Rabbit)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Rabbit)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Mouse)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	971	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Mouse)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Mouse)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	232	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18525 (N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair