BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM185306 US10011588, Example 125::US10689373, Example 125::US9156829, 125

SMILES: CCc1nc(cnc1N[C@H]1CCC[C@@H]1NC(=O)c1ncccc1-n1nccn1)C(F)(F)F

InChI Key: InChIKey=UFGCLPDMIZHEED-UHFFFAOYSA-N

Data: 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 185306
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Human)	BDBM185306 (US9156829, 125 \| US10011588, Example 125 \| US10689...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM185306 (US9156829, 125 \| US10011588, Example 125 \| US10689...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM185306 (US9156829, 125 \| US10011588, Example 125 \| US10689...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM185306 (US9156829, 125 \| US10011588, Example 125 \| US10689...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Human)	BDBM185306 (US9156829, 125 \| US10011588, Example 125 \| US10689...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Orexin receptor type 2 (Human)	BDBM185306 (US9156829, 125 \| US10011588, Example 125 \| US10689...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair