BDBM185376 US9156845, 19
SMILES OCC1CCN(CC1)c1ncnc2[nH]cc(-c3ccccc3)c12
InChI Key InChIKey=CLTLWPSRLYCESA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 185376
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 29nMpH: 7.5Assay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMpH: 7.5Assay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat # PV4874) was incu...More data for this Ligand-Target Pair