BDBM18538 8-ethyl-4-(trifluoromethyl)-1H,2H,6H,7H,8H,9H-pyrido[3,2-g]quinolin-2-one::tricyclic quinoline compound, 6 (+/-)

SMILES CCC1CCc2cc3c(cc(=O)[nH]c3cc2N1)C(F)(F)F

InChI Key InChIKey=ULQSKZMHFWEHRP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18538   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18538(8-ethyl-4-(trifluoromethyl)-1H,2H,6H,7H,8H,9H-pyri...)
Affinity DataKi:  11nM ΔG°:  -11.3kcal/mole IC50:  14nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed