BDBM185670 DAS-DFGO-I::N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

SMILES: Cc1nc(cc(n1)N2CCN(CC2)CCO)Nc3ncc(s3)C(=O)Nc4cccc(c4)NC(=O)c5cccc(c5)C(F)(F)F

InChI Key: InChIKey=GWJVXYZDNRXACJ-UHFFFAOYSA-N

Data: 3 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 185670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src [251-533] (Chicken)	BDBM185670 (DAS-DFGO-I | N-(2-chloro-6-methylphenyl)-2-[[6-[4-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [229-512] (Human)	BDBM185670 (DAS-DFGO-I | N-(2-chloro-6-methylphenyl)-2-[[6-[4-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 [229-512] (Human)	BDBM185670 (DAS-DFGO-I | N-(2-chloro-6-methylphenyl)-2-[[6-[4-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair