BDBM185690 UNC10000007::US9156822, 26

SMILES Clc1cccc(N2CCN(CC3CCC(COc4ccc5CCC(=O)Nc5c4)CC3)CC2)c1Cl

InChI Key InChIKey=CRARFJICFRVCGK-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 185690   

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM185690(UNC10000007 | US9156822, 26)
Affinity DataKi:  145nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM185690(UNC10000007 | US9156822, 26)
Affinity DataEC50:  2.10E+3nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

US Patent
LigandPNGBDBM185690(UNC10000007 | US9156822, 26)
Affinity DataEC50:  4.60E+4nMpH: 7.4Assay Description:HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent