BDBM185700 US10875847, Compound Oclacitinib::US9161939, 1a::US9271981, 1a

SMILES: CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1ncnc2[nH]ccc12

InChI Key: InChIKey=HJWLJNBZVZDLAQ-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 185700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.53	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
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Tyrosine-protein kinase JAK2 (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.5	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95.1	n/a	n/a	n/a	n/a	7.4	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75.1	n/a	n/a	n/a	n/a	7.4	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 [852-1142] (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.53	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 [809-1153] (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.5	n/a	n/a	n/a	n/a	7.4	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 [781-1124] (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95.1	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 [870-1187] (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75.1	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM185700 (US9271981, 1a | US9161939, 1a | US10875847, Compou...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair