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BDBM186185 US9163013, 2

SMILES: COc1ccc(CCN2CCC(CNC(=O)c3n[nH]c4ccc(OC)cc34)CC2)cc1

InChI Key: InChIKey=DAAZHWRRHXMDRD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186185   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM186185
PNG
(US9163013, 2)
Show SMILES COc1ccc(CCN2CCC(CNC(=O)c3n[nH]c4ccc(OC)cc34)CC2)cc1
Show InChI InChI=1S/C24H30N4O3/c1-30-19-5-3-17(4-6-19)9-12-28-13-10-18(11-14-28)16-25-24(29)23-21-15-20(31-2)7-8-22(21)26-27-23/h3-8,15,18H,9-14,16H2,1-2H3,(H,25,29)(H,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 560n/an/an/an/an/a22



AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.

US Patent


Assay Description
Activity on human GSK-3beta was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screenin...


US Patent US9163013 (2015)


BindingDB Entry DOI: 10.7270/Q2PN94DT
More data for this
Ligand-Target Pair