BDBM186314 US9670142, A155 6-(6-chloro-benzoxazol-2-yl)-pyridazine-3-carboxylic acid methyl-((1R,3S)-3-propionylamino-cyclopentyl)-amide

SMILES CCC(=O)N[C@H]1CC[C@H](C1)N(C)C(=O)c1ccc(nn1)-c1nc2ccc(Cl)cc2o1

InChI Key InChIKey=WMOUNSYMZCAJFC-UONOGXRCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186314   

TargetFatty acid synthase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM186314(US9670142, A155 6-(6-chloro-benzoxazol-2-yl)-pyrid...)
Affinity DataIC50:  2.65E+4nMpH: 7.0 T: 2°CAssay Description:The biochemical FASN activity testing was performed as 384 well two-time-point kinetic fluorescence intensity assay format in Greiner low volume medi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent