BDBM186378 US9163021, 35::US9163021, 65

SMILES CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(cc3)C(F)(F)F)c2)c2cnccc12

InChI Key InChIKey=KULCYZOAYJNEOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 186378   

TargetHigh affinity nerve growth factor receptor(Human)
Pfizer

US Patent
LigandPNGBDBM186378(US9163021, 35 | US9163021, 65)
Affinity DataIC50: 37nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Pfizer

US Patent
LigandPNGBDBM186378(US9163021, 35 | US9163021, 65)
Affinity DataIC50: 87.9nMAssay Description:Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent