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BDBM186504 US9163021, 167

SMILES: CC(C)n1cc(C(=O)c2ccnc(NC(=O)Cc3sc(C)nc3C)c2)c2cnccc12

InChI Key: InChIKey=GQBTWIGJRXVIBJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186504   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM186504
PNG
(US9163021, 167)
Show SMILES CC(C)n1cc(C(=O)c2ccnc(NC(=O)Cc3sc(C)nc3C)c2)c2cnccc12
Show InChI InChI=1S/C23H23N5O2S/c1-13(2)28-12-18(17-11-24-7-6-19(17)28)23(30)16-5-8-25-21(9-16)27-22(29)10-20-14(3)26-15(4)31-20/h5-9,11-13H,10H2,1-4H3,(H,25,27,29)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 181n/an/an/an/an/an/a



Pfizer Inc

US Patent


Assay Description
Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat#62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sou...


US Patent US9163021 (2015)


BindingDB Entry DOI: 10.7270/Q29C6W7C
More data for this
Ligand-Target Pair