BDBM18678 (2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorobenzene)sulfonyl]-2-hydroxy-2-methylpropanamide::(R)-Bicalutamide::CHEMBL63560::US10806720, Compound R-Bicalutamide::US11230523, Compound R-Bicalutamide::US11648234, Compound R-Bicalutamide::US20230382870, (R) Bicalutumide

SMILES: C[C@](O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key: InChIKey=LKJPYSCBVHEWIU-UHFFFAOYSA-N

Data: 14 KI  13 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 18678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor [633-919] (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		11	-10.1	n/a	n/a	1.00E+3	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		11	-10.1	n/a	n/a	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		11	-10.1	n/a	n/a	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		11	-10.1	n/a	n/a	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		509	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		509	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor [633-919] (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		509	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor [633-919] (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		509	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		509	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		509	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		518	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18678 (CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair