BDBM186911 US9670157, 77 5-Benzyl-1-ethyl-4-methyl-1H-pyrrole-2-carboxylic acid 4-aminomethyl-benzylamide::US9834513, 78

SMILES CCCn1c(Cc2ccccc2)c(C)cc1C(=O)NCc1ccc(CN)cc1

InChI Key InChIKey=TXFLOUBVCQUPIW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 186911   

TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM186911(US9670157, 77 5-Benzyl-1-ethyl-4-methyl-1H-pyrrole...)
Affinity DataIC50:  3.72E+3nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKallikrein-1(Homo sapiens (Human))
Kalvista Pharmceuticals

US Patent
LigandPNGBDBM186911(US9670157, 77 5-Benzyl-1-ethyl-4-methyl-1H-pyrrole...)
Affinity DataIC50:  1.00E+4nMAssay Description:KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM186911(US9670157, 77 5-Benzyl-1-ethyl-4-methyl-1H-pyrrole...)
Affinity DataIC50:  4.13E+3nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKallikrein-1(Homo sapiens (Human))
Kalvista Pharmceuticals

US Patent
LigandPNGBDBM186911(US9670157, 77 5-Benzyl-1-ethyl-4-methyl-1H-pyrrole...)
Affinity DataIC50: >1.00E+4nMAssay Description:KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent