BDBM18627 (10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one::Mifeprex::Mifepristone::RU-486::RU486 (tetramethyl-rhodamine conjugated)

SMILES: CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C

InChI Key: InChIKey=VKHAHZOOUSRJNA-UHFFFAOYSA-N

Data: 44 KI  134 IC50  2 Kd  13 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 197 hits for monomerid = 18627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.600	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	4.80	n/a	n/a	8.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Rat)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	8.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90	n/a	n/a	n/a	n/a	8.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80	n/a	n/a	n/a	n/a	8.0	4
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					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	8.0	4
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ATP-binding cassette sub-family C member 2 (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0730	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Pig)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Dog)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Pig)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Dog)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Rat)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Rat)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
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Protein cereblon/CUL4A/AR (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Rat)	BDBM18627 (Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair