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BDBM187329 US9169240, 68

SMILES: OCC[C@@H](Nc1nnc(o1)C(=O)c1nc2ccc(cc2s1)-c1ccccc1)C(O)=O

InChI Key: InChIKey=VVEBXPYNTJUXMO-YQTOOIBONA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187329   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))
BDBM187329
PNG
(US9169240, 68)
Show SMILES OCC[C@@H](Nc1nnc(o1)C(=O)c1nc2ccc(cc2s1)-c1ccccc1)C(O)=O
Show InChI InChI=1/C20H16N4O5S/c25-9-8-14(19(27)28)22-20-24-23-17(29-20)16(26)18-21-13-7-6-12(10-15(13)30-18)11-4-2-1-3-5-11/h1-7,10,14,25H,8-9H2,(H,22,24)(H,27,28)/t14-/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 27n/an/an/an/a8.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The enzymatic assay was measured using white, opaque 96-well half area plates. Each well contained 60 μL of assay buffer (50 mM HEPES pH 8.0, 50...


US Patent US9169240 (2015)


BindingDB Entry DOI: 10.7270/Q2W66JK8
More data for this
Ligand-Target Pair