BDBM18773 1,2-naphthalein derivative, 6::3,3-bis[4-hydroxy-2-methyl-5-(propan-2-yl)phenyl]-4-oxatricyclo[7.4.0.0^{2,6}]trideca-1(9),2(6),7,10,12-pentaen-5-one

SMILES CC(C)c1cc(c(C)cc1O)C1(OC(=O)c2ccc3ccccc3c12)c1cc(C(C)C)c(O)cc1C

InChI Key InChIKey=ZVPGVHLZYWNODB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18773   

TargetDihydrofolate reductase(Human)
Unimore

LigandChemical structure of BindingDB Monomer ID 18773BDBM18773(3,3-bis[4-hydroxy-2-methyl-5-(propan-2-yl)phenyl]-...)
Affinity DataKi:  1.30E+4nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed