BDBM18774 5-(4-chlorophenyl)pyrimidine-2,4-diamine::CHEMBL279492::P25

SMILES: Nc1ncc(c(N)n1)-c1ccc(Cl)cc1

InChI Key: InChIKey=OBYDYFKZLKCNOC-UHFFFAOYSA-N

Data: 6 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 18774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18774 (5-(4-chlorophenyl)pyrimidine-2,4-diamine | CHEMBL2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18774 (5-(4-chlorophenyl)pyrimidine-2,4-diamine | CHEMBL2...) Show SMILES Show InChI	GoogleScholar	UniChem		0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18774 (5-(4-chlorophenyl)pyrimidine-2,4-diamine | CHEMBL2...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (malaria parasite P. vivax)	BDBM18774 (5-(4-chlorophenyl)pyrimidine-2,4-diamine | CHEMBL2...) Show SMILES Show InChI	GoogleScholar	UniChem		3.42	-11.5	1.52E+3	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18774 (5-(4-chlorophenyl)pyrimidine-2,4-diamine | CHEMBL2...) Show SMILES Show InChI	GoogleScholar	UniChem		369	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18774 (5-(4-chlorophenyl)pyrimidine-2,4-diamine | CHEMBL2...) Show SMILES Show InChI	GoogleScholar	UniChem		556	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N] (malaria parasite P. vivax)	BDBM18774 (5-(4-chlorophenyl)pyrimidine-2,4-diamine | CHEMBL2...) Show SMILES Show InChI	GoogleScholar	UniChem		1.08E+3	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair