BDBM18779 6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine::CHEMBL21778::P17

SMILES: CCc1nc(N)nc(N)c1-c1ccc(C)cc1

InChI Key: InChIKey=BGGIEUCLTOKUIN-UHFFFAOYSA-N

Data: 10 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 18779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-hexosaminidase subunit alpha (Human)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bifunctional dihydrofolate reductase-thymidylate synthase (malaria parasite P. vivax)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		0.390	-12.8	140	n/a	n/a	n/a	n/a	7.0	25
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N] (malaria parasite P. vivax)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		2.21	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		10.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		14.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18779 (6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...) Show SMILES Show InChI	GoogleScholar	UniChem		284	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair