BDBM1878 N-(2-Phenethyl)-N -(2-(4-(ethoxycarbonyl)thiazolyl))thiourea::PETT Analog 45::ethyl 2-{[(2-phenylethyl)carbamothioyl]amino}-1,3-thiazole-4-carboxylate

SMILES CCOC(=O)c1csc(NC(=S)NCCc2ccccc2)n1

InChI Key InChIKey=GRNPPPWDQOYTKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1878   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1878(N-(2-Phenethyl)-N -(2-(4-(ethoxycarbonyl)thiazolyl...)
Affinity DataIC50:  200nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed