BDBM18782 5-(4-tert-butylphenyl)-6-ethylpyrimidine-2,4-diamine::CHEMBL21885::P23

SMILES: CCc1nc(N)nc(N)c1-c1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=FIUYJLCASFMHJV-UHFFFAOYSA-N

Data: 6 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 18782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18782 (5-(4-tert-butylphenyl)-6-ethylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18782 (5-(4-tert-butylphenyl)-6-ethylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18782 (5-(4-tert-butylphenyl)-6-ethylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		0.770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (malaria parasite P. vivax)	BDBM18782 (5-(4-tert-butylphenyl)-6-ethylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		1.14	-12.2	1.76E+3	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N] (malaria parasite P. vivax)	BDBM18782 (5-(4-tert-butylphenyl)-6-ethylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		47.5	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18782 (5-(4-tert-butylphenyl)-6-ethylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		66.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18782 (5-(4-tert-butylphenyl)-6-ethylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair