BDBM187879 US9169252, 420

SMILES CC(C)Nc1cc(ncc1C(=O)N[C@H]1CC[C@](F)(CC1)c1nccn1C)-n1ccc2cc(cnc12)C#N

InChI Key InChIKey=QDWQIFYUQWTYNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 187879   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187879(US9169252, 420)
Affinity DataIC50: 4.40nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent