BDBM18788 6-ethyl-5-phenylpyrimidine-2,4-diamine::CHEMBL22148::P20

SMILES: CCc1nc(N)nc(N)c1-c1ccccc1

InChI Key: InChIKey=XREDUPOVEQDQQS-UHFFFAOYSA-N

Data: 11 KI  10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 18788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-hexosaminidase subunit alpha (Human)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	4.5	n/a
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					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit beta (Human)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	4.5	n/a
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					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Human)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	4.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Human)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	4.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Human)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit beta (Human)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	7.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Human)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (malaria parasite P. vivax)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0300	-14.3	1.82E+3	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N] (malaria parasite P. vivax)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0800	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18788 (CHEMBL22148 | 6-ethyl-5-phenylpyrimidine-2,4-diami...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair