BDBM18789 6-methyl-5-phenylpyrimidine-2,4-diamine::CHEMBL21408::P36

SMILES: Cc1nc(N)nc(N)c1-c1ccccc1

InChI Key: InChIKey=RBOOBZAJMOATAV-UHFFFAOYSA-N

Data: 6 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 18789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18789 (CHEMBL21408 | 6-methyl-5-phenylpyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (malaria parasite P. vivax)	BDBM18789 (CHEMBL21408 | 6-methyl-5-phenylpyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		4.18	-11.4	1.13E+4	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18789 (CHEMBL21408 | 6-methyl-5-phenylpyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		10.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N] (malaria parasite P. vivax)	BDBM18789 (CHEMBL21408 | 6-methyl-5-phenylpyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		22.5	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18789 (CHEMBL21408 | 6-methyl-5-phenylpyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		25.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18789 (CHEMBL21408 | 6-methyl-5-phenylpyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		36.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM18789 (CHEMBL21408 | 6-methyl-5-phenylpyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair