BDBM187992 US9169252, 532::US9169252, 534

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1N[C@@H]1CCN(C1)c1ncc(F)cn1)-n1ncc2cc(cnc12)C#N

InChI Key InChIKey=SCXQOHWTUJZMSL-WIYYLYMNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 187992   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187992(US9169252, 532 | US9169252, 534)
Affinity DataIC50:  1.5nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM187992(US9169252, 532 | US9169252, 534)
Affinity DataIC50:  5.5nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent