BDBM188060 US9169252, 594::US9169252, 596

SMILES CC(C)C(O)CNc1cc(ncc1C(=O)NC[C@@H](F)C(C)(C)O)-n1ncc2cc(Cl)cnc12

InChI Key InChIKey=JBMSAMOLSRLBBB-QRWMCTBCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 188060   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM188060(US9169252, 594 | US9169252, 596)
Affinity DataIC50:  18.2nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM188060(US9169252, 594 | US9169252, 596)
Affinity DataIC50:  17.5nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent