BDBM188087 US9169252, 618::US9169252, 619::US9169252, 620::US9169252, 621

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1NC1CCC(F)C1)-n1ncc2cc(F)cnc12

InChI Key InChIKey=DYBZYXWEMQGBKG-LEHRNKBSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 188087   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM188087(US9169252, 618 | US9169252, 619 | US9169252, 620 |...)
Affinity DataIC50:  5.80nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM188087(US9169252, 618 | US9169252, 619 | US9169252, 620 |...)
Affinity DataIC50:  4nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM188087(US9169252, 618 | US9169252, 619 | US9169252, 620 |...)
Affinity DataIC50:  3.40nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM188087(US9169252, 618 | US9169252, 619 | US9169252, 620 |...)
Affinity DataIC50:  4nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent