BDBM188111 US9169252, 642::US9169252, 643

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1N[C@@H]1C[C@H]1CO)-n1ncc2cc(cnc12)C#N

InChI Key InChIKey=YPRBNMOLLIWNPY-YXJHDRRASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 188111   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM188111(US9169252, 642 | US9169252, 643)
Affinity DataIC50:  5.40nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM188111(US9169252, 642 | US9169252, 643)
Affinity DataIC50:  4.80nMpH: 7.2Assay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 L prepared from 15 L additions of enzyme and substrates (fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent