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BDBM188180 US9169259, I-63

SMILES: CC1CCCN1c1cccc(Nc2cc(nn3ccnc23)-c2ccc3CCCNc3c2)n1

InChI Key: InChIKey=BEBJVQGCFRJPNR-UHFFFAOYNA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188180   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SYK RPA purified, truncated construct of Spleen Tyrosine Kinase aa 360-635


(Homo sapiens (Human))
BDBM188180
PNG
(US9169259, I-63)
Show SMILES CC1CCCN1c1cccc(Nc2cc(nn3ccnc23)-c2ccc3CCCNc3c2)n1
Show InChI InChI=1/C25H27N7/c1-17-5-4-13-31(17)24-8-2-7-23(29-24)28-22-16-21(30-32-14-12-27-25(22)32)19-10-9-18-6-3-11-26-20(18)15-19/h2,7-10,12,14-17,26H,3-6,11,13H2,1H3,(H,28,29)
PDB

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 151n/an/an/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...


US Patent US9169259 (2015)


BindingDB Entry DOI: 10.7270/Q2H130S2
More data for this
Ligand-Target Pair