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BDBM188353 US9169224, 35

SMILES: O=C(Nc1ccccc1)N1CCN(Cc2ccc3OCCOc3c2)CC1

InChI Key: InChIKey=IORNRLOPPQQIRT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188353   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM188353
PNG
(US9169224, 35)
Show SMILES O=C(Nc1ccccc1)N1CCN(Cc2ccc3OCCOc3c2)CC1
Show InChI InChI=1S/C20H23N3O3/c24-20(21-17-4-2-1-3-5-17)23-10-8-22(9-11-23)15-16-6-7-18-19(14-16)26-13-12-25-18/h1-7,14H,8-13,15H2,(H,21,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 460n/an/an/an/a9.0n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....


US Patent US9169224 (2015)


BindingDB Entry DOI: 10.7270/Q24Q7ST1
More data for this
Ligand-Target Pair