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BDBM188398 US9169224, 87

SMILES: COc1cccc(NC(=O)N2CCN(Cc3ccc(Br)c(Br)c3)CC2)c1

InChI Key: InChIKey=PIEPIIIIPKAINW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188398   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM188398
PNG
(US9169224, 87)
Show SMILES COc1cccc(NC(=O)N2CCN(Cc3ccc(Br)c(Br)c3)CC2)c1
Show InChI InChI=1S/C19H21Br2N3O2/c1-26-16-4-2-3-15(12-16)22-19(25)24-9-7-23(8-10-24)13-14-5-6-17(20)18(21)11-14/h2-6,11-12H,7-10,13H2,1H3,(H,22,25)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 48n/an/an/an/a9.0n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....


US Patent US9169224 (2015)


BindingDB Entry DOI: 10.7270/Q24Q7ST1
More data for this
Ligand-Target Pair