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BDBM188443 US9169224, 132

SMILES: O=C(Nc1ccccc1)N1CCN(Cc2cccc(Oc3cc4ccccc4c4ccccc34)c2)CC1

InChI Key: InChIKey=LKMDMRKBURTLPM-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188443   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM188443
PNG
(US9169224, 132)
Show SMILES O=C(Nc1ccccc1)N1CCN(Cc2cccc(Oc3cc4ccccc4c4ccccc34)c2)CC1
Show InChI InChI=1S/C32H29N3O2/c36-32(33-26-11-2-1-3-12-26)35-19-17-34(18-20-35)23-24-9-8-13-27(21-24)37-31-22-25-10-4-5-14-28(25)29-15-6-7-16-30(29)31/h1-16,21-22H,17-20,23H2,(H,33,36)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.00E+3n/an/an/an/a9.0n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....


US Patent US9169224 (2015)


BindingDB Entry DOI: 10.7270/Q24Q7ST1
More data for this
Ligand-Target Pair