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BDBM188681 US9169246, 221

SMILES: CCN(CCN(C)C)C(=O)c1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1

InChI Key: InChIKey=PBXWEPKSIAWIGS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188681   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM188681
PNG
(US9169246, 221)
Show SMILES CCN(CCN(C)C)C(=O)c1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1
Show InChI InChI=1S/C24H25F3N6O2/c1-4-32(11-10-31(2)3)23(35)21-16(6-5-9-28-21)15-7-8-17-19(12-15)33(14-24(25,26)27)22(34)18-13-29-30-20(17)18/h5-9,12-13H,4,10-11,14H2,1-3H3,(H,29,30)
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MMDB

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PC sid
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Similars

US Patent
n/an/a 71.4n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...


US Patent US9169246 (2015)


BindingDB Entry DOI: 10.7270/Q2B856XZ
More data for this
Ligand-Target Pair