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BDBM188728 US9169246, 270

SMILES: CN1CCCN(CC1)c1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1

InChI Key: InChIKey=BXIWZIGZDBEFJN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 188728   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM188728
PNG
(US9169246, 270)
Show SMILES CN1CCCN(CC1)c1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1
Show InChI InChI=1S/C23H23F3N6O/c1-30-8-3-9-31(11-10-30)21-16(4-2-7-27-21)15-5-6-17-19(12-15)32(14-23(24,25)26)22(33)18-13-28-29-20(17)18/h2,4-7,12-13H,3,8-11,14H2,1H3,(H,28,29)
PDB
MMDB

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Similars

US Patent
n/an/a 6n/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The enzymatic test is a test in two steps.In a first step, it consists in placing in contact the compound according to the invention, the dialysed Me...


US Patent US9169246 (2015)


BindingDB Entry DOI: 10.7270/Q2B856XZ
More data for this
Ligand-Target Pair