BDBM18885 2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(propan-2-yl)phenyl}methyl)-3,5-dimethylphenoxy]acetic acid::CHEMBL109279::JMC496635 Compound 5::thyromimetic, 5b

SMILES: CC(C)c1cc(Cc2c(C)cc(OCC(O)=O)cc2C)cc(C#Cc2ccc(cc2)[N+]([O-])=O)c1O

InChI Key: InChIKey=IXMROOKFPWGDGF-UHFFFAOYSA-N

Data: 6 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 18885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor alpha (Human)	BDBM18885 (JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	93	n/a	n/a	n/a	n/a	7.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Human)	BDBM18885 (JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	7.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Human)	BDBM18885 (JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	93	n/a	n/a	n/a	n/a	7.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Human)	BDBM18885 (JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	7.0	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Human)	BDBM18885 (JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Human)	BDBM18885 (JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Human)	BDBM18885 (JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Human)	BDBM18885 (JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair