BDBM18906 3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i::3-[3,5-dibromo-4-(hexyloxy)phenyl]propanoic acid

SMILES CCCCCCOc1c(Br)cc(CCC(O)=O)cc1Br

InChI Key InChIKey=FVDRTJXVCUAOCA-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18906   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18906(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i | 3-[3...)
Affinity DataIC50:  1.10E+3nM EC50:  0.600nMpH: 7.0 T: 2°CAssay Description:IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18906(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i | 3-[3...)
Affinity DataIC50:  360nM EC50:  1nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18906(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i | 3-[3...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18906(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i | 3-[3...)
Affinity DataIC50:  363nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18906(3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i | 3-[3...)
Affinity DataIC50:  363nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed