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BDBM189308 US9173884, BC11-19-3

SMILES: Cc1ccc2c(c1)sc1nc(=O)n(-c3cccc(Cl)c3)c(=O)n21

InChI Key: InChIKey=TWFOMURCRPDYHN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189308   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 11A (PDE11A)


(Homo sapiens (Human))
BDBM189308
PNG
(US9173884, BC11-19-3)
Show SMILES Cc1ccc2c(c1)sc1nc(=O)n(-c3cccc(Cl)c3)c(=O)n21
Show InChI InChI=1S/C16H10ClN3O2S/c1-9-5-6-12-13(7-9)23-15-18-14(21)19(16(22)20(12)15)11-4-2-3-10(17)8-11/h2-8H,1H3
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>2.00E+6n/an/an/an/an/an/a



Boston College

US Patent


Assay Description
In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...


US Patent US9173884 (2015)


BindingDB Entry DOI: 10.7270/Q2PK0DZ6
More data for this
Ligand-Target Pair