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BDBM189380 5-methyl-4-(2-thiazolylazo)resorcinol::PTK66

SMILES: Cc1cc(O)cc(O)c1\N=N\c1nccs1

InChI Key: InChIKey=LABKTXRFMJIJAU-OUKQBFOZSA-N

Data: 2 Kd  2 ITC

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 189380   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aurora kinase B/Inner centromere protein


(Homo sapiens (Human))
BDBM189380
PNG
(5-methyl-4-(2-thiazolylazo)resorcinol | PTK66)
Show SMILES Cc1cc(O)cc(O)c1\N=N\c1nccs1
Show InChI InChI=1S/C10H9N3O2S/c1-6-4-7(14)5-8(15)9(6)12-13-10-11-2-3-16-10/h2-5,14-15H,1H3/b13-12+
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 500n/an/an/a8.025



Jawaharlal Nehru Centre for Advanced Scientific Research



Assay Description
Calorimetric titrations were performed in a Microcal iTC 200 microcalorimeter. Freshly purified 5 ÁM protein (Aurora A/B kinases) was titrated agains...


Chem Biol Drug Des 87: 958-67 (2016)

More data for this
Ligand-Target Pair
Aurora kinase B/Inner centromere protein


(Homo sapiens (Human))
BDBM189380
PNG
(5-methyl-4-(2-thiazolylazo)resorcinol | PTK66)
Show SMILES Cc1cc(O)cc(O)c1\N=N\c1nccs1
Show InChI InChI=1S/C10H9N3O2S/c1-6-4-7(14)5-8(15)9(6)12-13-10-11-2-3-16-10/h2-5,14-15H,1H3/b13-12+
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.75E+3n/an/an/a8.025



Jawaharlal Nehru Centre for Advanced Scientific Research



Assay Description
Calorimetric titrations were performed in a Microcal iTC 200 microcalorimeter. Freshly purified 5 ÁM protein (Aurora A/B kinases) was titrated agains...


Chem Biol Drug Des 87: 958-67 (2016)

More data for this
Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 189380
Cell (A)Syringe (B)Cell
Links
Syringe
Links
Cell + Syr
Links
ΔG°
kcal/mole
-TΔS°
kcal/mole
ΔH°
kcal/mole
log KpHTemp
°C
Serine/threonine-protein kinase Aurora-B

(Homo sapiens (Human))
BDBM189380
JPEG
(5-methyl-4-(2-thiazolylazo)resorcinol | PTK66)
GoogleScholar
PDB
PC cid
PC sid
-7.886.02-13.95.78825



Jawaharlal Nehru Centre for Advanced Scientific Research





Chem Biol Drug Des 87: 958-67 (2016)

Serine/threonine-protein kinase Aurora-B

(Homo sapiens (Human))
BDBM189380
JPEG
(5-methyl-4-(2-thiazolylazo)resorcinol | PTK66)
GoogleScholar
PDB
PC cid
PC sid
-9.315.45-25.86.83825



Jawaharlal Nehru Centre for Advanced Scientific Research





Chem Biol Drug Des 87: 958-67 (2016)