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BDBM189391 3-((1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl)oxazolo[4,5-b]pyridin-2(3H)-one (4k)

SMILES: Clc1cccc(c1)-n1cc(Cn2c3ncccc3oc2=O)nn1

InChI Key: InChIKey=SPEQYHFSCFOWTM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189391   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Axin-1/Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM189391
PNG
(3-((1-(3-chlorophenyl)-1H-1,2,3-triazol-4-yl)methy...)
Show SMILES Clc1cccc(c1)-n1cc(Cn2c3ncccc3oc2=O)nn1
Show InChI InChI=1S/C15H10ClN5O2/c16-10-3-1-4-12(7-10)21-9-11(18-19-21)8-20-14-13(23-15(20)22)5-2-6-17-14/h1-7,9H,8H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.84E+4n/an/an/an/an/a30



Hamdard University (Jamia Hamdard)



Assay Description
In a typical assay, 10 L of test compound of different concentrations (dissolvedin dimethyl sulfoxide [DMSO] and diluted with assay buffer) and 10 ...


Chem Biol Drug Des 87: 918-26 (2016)


Article DOI: 10.1111/cbdd.12724
BindingDB Entry DOI: 10.7270/Q28914NR
More data for this
Ligand-Target Pair