BDBM189877 US10227346, Example 5::US10426135, Example 5::US9670201, 5 3-cyano-N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide::US9920054, Example 5

SMILES: CC(C)C(=O)N1CCC(CC1)c1cn(C)c2ncc(NC(=O)c3cccc(c3)C#N)c(c12)C(F)(F)F

InChI Key: InChIKey=BIHPJIJLDNUDGH-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 189877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Human)	BDBM189877 (US9670201, 5 3-cyano-N-(3-(1-isobutyrylpiperidin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	25
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Nuclear receptor ROR-gamma (Human)	BDBM189877 (US9670201, 5 3-cyano-N-(3-(1-isobutyrylpiperidin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16.6	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-gamma (Human)	BDBM189877 (US9670201, 5 3-cyano-N-(3-(1-isobutyrylpiperidin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16.6	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-gamma (Human)	BDBM189877 (US9670201, 5 3-cyano-N-(3-(1-isobutyrylpiperidin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16.6	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-gamma (Human)	BDBM189877 (US9670201, 5 3-cyano-N-(3-(1-isobutyrylpiperidin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-gamma (Human)	BDBM189877 (US9670201, 5 3-cyano-N-(3-(1-isobutyrylpiperidin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor ROR-gamma (Mouse)	BDBM189877 (US9670201, 5 3-cyano-N-(3-(1-isobutyrylpiperidin-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair