BDBM190112 US9175003, 338

SMILES: Cc1ccccc1NC(=O)N1Cc2cc3O[C@H](COc3cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(Oc2ccnc(C)c2C)cc1)C(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1

InChI Key: InChIKey=ZZKYPRYFWCAKIB-CYGWCNTOSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (GLP-1) (Homo sapiens (Human))	BDBM190112 (US9175003, 338) Show SMILES Cc1ccccc1NC(=O)N1Cc2cc3O[C@H](COc3cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(Oc2ccnc(C)c2C)cc1)C(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C49H44Cl2N4O8/c1-28-6-4-5-7-40(28)54-49(59)55-25-35-24-45-44(61-27-46(63-45)33-11-15-36(16-12-33)60-26-32-10-17-38(50)39(51)20-32)23-34(35)22-42(55)47(56)53-41(48(57)58)21-31-8-13-37(14-9-31)62-43-18-19-52-30(3)29(43)2/h4-20,23-24,41-42,46H,21-22,25-27H2,1-3H3,(H,53,56)(H,54,59)(H,57,58)/t41-,42-,46+/m0/s1	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	377	n/a	n/a	n/a	n/a
vTv Therapeutics LLC US Patent					Assay Description The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...				US Patent US9175003 (2015) BindingDB Entry DOI: 10.7270/Q27943FG
					More data for this Ligand-Target Pair