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BDBM190537 US9181184, 24

SMILES: OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1C([N+]#[C-])c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=BYVOHQZFZXGRCZ-DYPLGBCKSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190537   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
alpha-glucosidase (Gaa)


(Mus musculus (Mouse))
BDBM190537
PNG
(US9181184, 24)
Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1C([N+]#[C-])c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C15H17F3N2O4/c1-19-14(8-2-4-9(5-3-8)15(16,17)18)20-6-11(22)13(24)12(23)10(20)7-21/h2-5,10-14,21-24H,6-7H2/t10-,11+,12-,13-,14?/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/an/an/a 7.71E+4n/an/an/an/a



Amicus Therapeutics, Inc.

US Patent


Assay Description
Cells were washed two times with 200 μL dPBS followed by the addition of 70 μL of substrate (2.11 mM 3 mM 4-MU-α-D-glu) in citrate-pho...


US Patent US9181184 (2015)


BindingDB Entry DOI: 10.7270/Q2T43RWB
More data for this
Ligand-Target Pair